Yes, you can use Bitcoin to gamble. There are a number of online casinos that accept Bitcoin as a form of payment, and there are also a number of Bitcoin-specific gambling sites. However, it is important to note that gambling with Bitcoin is not regulated in the same way as traditional gambling.
This means that there is no guarantee that you will be able to withdraw your winnings or that the site will even stay in operation. If you do choose to gamble with Bitcoin, be sure to research the site thoroughly before depositing any money.