Assuming you’re talking about cashing out your cryptocurrency to fiat (e.g. USD, EUR, GBP), there are a few ways to do this depending on which exchange you’re using.
If you’re using Coinbase, for example, you can link your bank account and withdraw your funds that way. Or, if you’re using an exchange like Binance, you can withdraw to a fiat-backed stablecoin like Tether (USDT) or Paxos Standard Token (PAX) and then convert that back to fiat on an exchange like Kraken.
There are also services like BitPay that allow you to convert your cryptocurrency to fiat without having to go through an exchange.
Ultimately, the best way to cash out your cryptocurrency will depend on which assets you’re holding and how quickly you need access to the cash.